Black Fungus Mucormycosis; General and Homoeopathic management

Black Fungus Mucormycosis; General and Homoeopathic management

 



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Mucormycosis

Mucormycosis (previously called zygomycosis) is a serious but rare fungal infection caused by a group of molds called mucormycetes. These molds live throughout the environment. Mucormycosis mainly affects people who have health problems or take medicines that lower the body’s ability to fight germs and sickness. (CDC)

Causes of Black Fungus or Mucormycosis

Zygomycetes represent the general class of fungi that cause mucormycosis. Rhizopus arrhizus species from the Mucoraceae family are the most commonly identified cause of mucormycosis in humans. Other fungal causes may include Mucor species, Cunninghamella BertholletiaApophysomyces elegans, Absidia species, Saksenaea species, Rhizomucor pusillus, Entomophthora species, Conidiobolus species, and Basidiobolus species.

How does someone get mucormycosis?

People get mucormycosis through contact with fungal spores in the environment. For example, the lung or sinus forms of the infection can occur after someone inhales the spores from the air. A skin infection can occur after the fungus enters the skin through a scrape, burn, or other type of skin injury. (CDC)

Is mucormycosis contagious?

No. Mucormycosis can’t spread between people or between people and animals. (CDC)

 

Types of mucormycosis

  • Rhinocerebral (sinus and brain) mucormycosis infection in the sinuses that can spread to the brain. Most common in uncontrolled diabetes and in kidney transplant.
  • Pulmonary (lung) mucormycosis most common type people with cancer and an organ transplant or a stem cell transplant.
  • Gastrointestinal mucormycosis is more common among young children than adults, especially premature and low birth weight infants less than 1 month of age, who have had antibiotics, surgery, or medications that lower the body’s ability to fight germs and sickness. 9-10
  • Cutaneous (skin) mucormycosis: occurs after the fungi enter the body through a break in the skin (for example, after surgery, a burn, or other type of skin trauma).
  • Disseminated mucormycosis occurs when the infection spreads through the bloodstream to affect another part of the body. most commonly affects the brain, but also can affect other organs such as the spleen, heart, and skin. (CDC)


Symptomatology of Mucormycosis

 

Symptoms depend on where in the body the fungus is growing

Symptoms of rhinocerebral (sinus and brain) mucormycosis include:

  • One-sided facial swelling
  • Headache
  • Nasal or sinus congestion
  • Black lesions on nasal bridge or upper inside of mouth that quickly become more severe
  • Fever

Symptoms of pulmonary (lung) mucormycosis include:

  • Fever
  • Cough
  • Chest pain
  • Shortness of breath

Cutaneous (skin) mucormycosis 

·         Look like blisters or ulcers, and the infected area may turn black.

·         Other symptoms include pain, warmth, excessive redness, or swelling around a wound.

Symptoms of gastrointestinal mucormycosis include:

  • Abdominal pain
  • Nausea and vomiting
  • Gastrointestinal bleeding

Disseminated mucormycosis typically occurs in people who are already sick from other medical conditions, so it can be difficult to know which symptoms are related to mucormycosis. Patients with disseminated infection in the brain can develop mental status changes or coma.

(CDC)


Diagnosis

How is mucormycosis diagnosed?

·         Medical history, symptoms, physical examinations, and laboratory tests

·         Tissue biopsy,

·         Fungal culture.

·         Imaging tests; such as a CT scan of lungs, sinuses, or other parts of body, depending on the location of the suspected infection.                                                                             (CDC)

 

COVID-19-associated Mucormycosis

Commonly referred to as black fungus, is the association of mucormycosis (an aggressive fungal infection) with COVID-19.It has been reported around the nose, eyes and brain 

·        In these reports, the most common risk factor for mucormycosis was diabetes.

·       Most cases presented during hospitalization (often 10–14 days after admission),

·     COVID-associated mucormycosis has especially affected people in India. The association also appeared in Russia                                                                     

(Wikipedia)



Risk factors

Who gets mucormycosis?

Mucormycosis is rare, but it’s more common among people who have health problems or take medicines that lower the body’s ability to fight germs and sickness.

Certain groups of people are more likely to get mucormycosis, 1including people with:

  • Diabetes, especially with diabetic ketoacidosis
  • Cancer
  • Organ transplant
  • Stem cell transplant
  • Neutropenia pdf icon (low number of white blood cells)
  • Long-term corticosteroid use
  • Injection drug use
  • Too much iron in the body (iron overload or hemochromatosis)
  • Skin injury due to surgery, burns, or wounds
  • Prematurity and low birthweight (for neonatal gastrointestinal mucormycosis)

(CDC)


Complications of Mucormycosis

  • The complications of Mucormycosis or Black Fungus are serious
  • In addition, because surgical debridement is almost uniformly needed, some normal tissue may be destroyed because the surgeon must remove all tissue that is dead or dying.
  • An example is infection of the eye orbit; often the whole eye must be removed.
  • Consequently, serious complications may occur, such as


Treatment for Mucormycosis or Black Fungus

 

Conventional or Allopathic Treatment

·         Antifungal medicine, usually amphotericin B, posaconazole, or isavuconazole.

·         These medicines are given through a vein (amphotericin B, posaconazole, isavuconazole) or by mouth (posaconazole, isavuconazole).

·         Other medicines, including fluconazole, voriconazole, and echinocandins, do not work against fungi that cause mucormycosis.

·         Often, mucormycosis requires surgery in conventional treatment to cut away the infected tissue.

(CDC)



Homoeopathic Management for Black fungus or Mucormycosis

Indian ministry of AYUSH has formulated a guideline for prevention and treatment of Black Fungus or Mucormycosis Homoeopathically.


Homoeopathic Prevention

AYUSH guideline for prevention of Black Fungus –

Arsenic-Alb 200 (daily two times, six pills each time for 5 days) and

Five. Phos 6x tablets (twice daily, three tablets each time for 30 days). 


Homoeopathic Treatment

Since Homoeopathy is a system of medicine based on individualisation and Mucormycosis is not an exception, Physicians must go through individualistic presentation of each case strictly. AYUSH has formulated following treatment guideline for Black Fungus Homoeopathically


The following medicines as per the indications can be used individually one medicine at a time on the advice and under supervision of qualified Homoeopathic physician in the treatment of Mucormycosis, according to AYUSH


Rhinocerebral Mucormycosis, drug prescribed is Arsenic-Alb, Kali Bich, Merc.Iod. Rubrum, Merc. Iod. Flavum, Merc. Sol, Cinnabaris, Thuja, Carbo Animalis; 200 potency, daily two times 6 pills each time for 5 days.

 

Pulmonary Mucormycosis, drug is Arsenic-Alb, Phosphorous, Bryonia, Carbo Animalis, Ant.Tart; 200 potency, daily two times 6 pills each time for 5 days.

 

Cutaneous Mucormycosis, it is Arsenic-Alb, Sulphur, Merc. sol, Anthracinum; 200 potency, daily two times 6 pills each time for 5 days

 

Gastrointestinal Mucormycosis, it is Arsenic-Alb, Phosphorous, Nitric Acid; 200 potency, daily two times 6 pills each time for 5 days.

                                                                                                                    thehomoeopathy.in


Note- You have to take only one or two medicine according to registered Homoeopathic physician with detailed present medical case history and we prefer liquid form of medicine instead of pill forms. The above guideline is not the only protocol we follow. Here in our Kazy Homoeopathic Health Care we have our own guideline and protocol based on Basic Homoeopathic protocol, individualization and also the AYUSH and other authentic Homoeopathic guidelines and protocols.



Prognosis of Mucormycosis or Black Fungus

 

Conventional or Allopathic treatment

  • The prognosis of mucormycosis is usually fair to poor; the prognosis depends on the overall health of the patient, the speed of diagnosis and treatment, the patient's ability to respond to treatments, the complete debridement of the infected body area, and the body area that is initially infected.
  • For example, the mortality (death rate) of patients with rhinocerebral and GI mucormycosis is about 85% while the mortality rate for all patients with other types of mucormycosis is about 50%.
  • Patients who survive this dangerous infection often have disabilities related to the extent of tissue lost due to the fungal destruction and the necessary surgical debridement (blindness, limb loss, organ dysfunctions).

Medicine.net


Homoeopathic prognosis

Homoeopathic treatment frequently is healing black fungus like symptoms through proper individualization by Homoeopathic physician all over the world. At present it has become epidemic to various parts of India during the COVID 19 pandemic. Homoeopathic medicine very much effective in fungal infection.

Though there is not enough homoeopathic researches on Mucormycosis but has a long successful treatment history and clinical evidence in Homoeopathic literature and homoeopathic treatment culture of Black fungus like symptoms and other fungal infections.

 

Homoepathy is and can be a very effective treatment system in Balack Fangus or Mucormycosis . It can successfully cure the diseases through proper individualized treatment. However in some cases surgical debridement of infected area with Homoeopathic treatment. Homoeopathic treatment or combined treatment is expected to be better prognosis in Mucormycosis.


Refrences

CDC, medicine.net, Wikipedia, DNA India, thehomeopathy.in, Medical News Today etc 


Note- You have to take only one or two medicine according to registered Homoeopathic physician with detailed present medical case history and we prefer liquid form of medicine instead of pill forms. The above guideline is not the only protocol we follow. Surgical and other treatment procedures may need beside Homoeopathic treatment.   Here in our Kazy Homoeopathic Health Care we have our own guideline and protocol based on Basic Homoeopathic protocol, individualization and also the AYUSH and other authentic Homoeopathic guidelines and protocols.


Dr. Kazy Habib BHMS, MPH

General Homoeopathic Physician

Contact: 8801738618894 (call, Whats app, Imo)

Kazy Homoeopathic Treatment & Private Research Center

Kazy Homoeopathic Health Care


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